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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKH
All Species:
20
Human Site:
S761
Identified Species:
55
UniProt:
Q86XP1
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XP1
NP_690874.2
1220
134866
S761
F
I
D
P
D
L
D
S
V
D
G
Y
S
E
K
Chimpanzee
Pan troglodytes
XP_001151474
1220
134870
S761
F
I
D
P
D
P
D
S
V
D
G
Y
S
E
K
Rhesus Macaque
Macaca mulatta
XP_001114920
1167
129871
T710
P
F
N
S
E
P
E
T
L
E
Y
Y
T
E
K
Dog
Lupus familis
XP_534133
1182
132580
S723
F
I
D
P
D
P
D
S
V
D
G
Y
S
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507672
1254
138458
S794
F
I
D
P
D
P
D
S
L
E
G
Y
S
E
K
Chicken
Gallus gallus
XP_001232791
1333
149344
S873
F
I
D
P
D
P
D
S
L
E
G
Y
S
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108193
586
65385
C185
K
A
T
C
P
P
S
C
A
S
P
L
L
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A8JQ65
1895
211641
L1428
L
M
D
P
D
E
T
L
L
A
G
Y
H
E
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202627
1158
127377
K687
L
M
D
Q
D
T
E
K
V
E
G
F
S
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
62.2
90.7
N.A.
N.A.
N.A.
N.A.
82.3
76.8
N.A.
39
N.A.
34.9
N.A.
N.A.
51.5
Protein Similarity:
100
99.8
73.4
92.8
N.A.
N.A.
N.A.
N.A.
88.1
82.9
N.A.
43.2
N.A.
46.5
N.A.
N.A.
64.1
P-Site Identity:
100
93.3
20
93.3
N.A.
N.A.
N.A.
N.A.
80
80
N.A.
0
N.A.
46.6
N.A.
N.A.
40
P-Site Similarity:
100
93.3
66.6
93.3
N.A.
N.A.
N.A.
N.A.
93.3
93.3
N.A.
0
N.A.
60
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
0
0
0
12
12
0
0
0
0
0
% A
% Cys:
0
0
0
12
0
0
0
12
0
0
0
0
0
0
0
% C
% Asp:
0
0
78
0
78
0
56
0
0
34
0
0
0
0
0
% D
% Glu:
0
0
0
0
12
12
23
0
0
45
0
0
0
89
0
% E
% Phe:
56
12
0
0
0
0
0
0
0
0
0
12
0
0
12
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
78
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% H
% Ile:
0
56
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
0
0
0
0
0
0
12
0
0
0
0
0
0
78
% K
% Leu:
23
0
0
0
0
12
0
12
45
0
0
12
12
0
0
% L
% Met:
0
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
0
0
67
12
67
0
0
0
0
12
0
0
0
0
% P
% Gln:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
12
0
0
12
56
0
12
0
0
67
0
12
% S
% Thr:
0
0
12
0
0
12
12
12
0
0
0
0
12
0
0
% T
% Val:
0
0
0
0
0
0
0
0
45
0
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
12
78
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _